What are the most common forms of Cannabis testing?
There isn't just one form of testing which can be carried out to determine the 'quality' of cannabis to indicate if it is safe for human use. Everything from pesticides to heavy metals should be tested for.
Potency Testing
In potency testing cannabinoids are isolated and their strength and efficacy is evaluated. Over 100 different cannabinoids have been isolated from cannabis and their effects vary.
Chromatography (gas and liquid) is one of the most common methods used in potency testing. Some analytical instruments which can be used for cannabis potency testing include:
Instrument which can be used for Potency Testing | Peak Scientific recommended gas solution |
Agilent Intuvo 9000 GC | Precision Series |
Agilent 5977B GC/MSD | Precision Series |
Agilent 1290 Infinity II LC | Solaris 10 |
Agilent 1290 Infinity II 2D-LC Solution | Solaris 10 |
Agilent 1260 Infinity II SFC System | Solaris 10 |
Ellutia 200 Series GC | Precision Hydrogen Trace for carrier gas |
Thermo Fisher Q Exactive Hybrid Quadrupole-Orbitrap LC-MS Mass Spectrometer | Solaris XE 35, Genius XE 35, Genius 1022 |
Thermo Fisher TSQ Altis and TSQ Quantis Triple Quadrupole Mass Spectrometer LC-MS/MS Systems | Solaris XE 35, Genius XE 35 |
Thermo Fisher TRACE 1310 Gas Chromatograph | Precision Series |
Thermo Fisher ISQ 7000 Single Quadrupole GC-MS System | Precision Hydrogen Trace for carrier gas |
Thermo Fisher Q Exactive GC Orbitrap GC-MS/MS | Precision Nitrogen Trace and Precision Hydrogen Trace for carrier gas |
Thermo Fisher Exactive GC Orbitrap GC-MS Systems | Precision Hydrogen Trace for carrier gas |
SCIEX QET 4500 LC-MS/MS System | Genius 1024 |
If you require carrier gas or detector gas for cannabis potency testing, a gas generator from the Peak Scientific Precision series could be the ideal gas solution. To find out which gas generator we would recommend for your instrument and requirements, even if it is not listed above, please contact us.
The Precision Series of hydrogen, nitrogen and zero air generators for Gas Chromatography
Terpene testing
Terpenes are the volatile unsaturated hydrocarbons which are responsible for the odor of a cannabis sample. Every different strain of cannabis has it's own unique terpene composition.
Gas chromatography and liquid chromatography are also commonly used for terpene testing. Some of the instruments which can be used for terpene testing include:
Instrument which can be used for Terpene testing | Peak Scientific recommended gas solution |
Shimadzu GCMS-TQ8050 Triple Quadrupole Gas Chromatograph Mass Spectrometer | Precision Series |
Shimadzu GCMS-QP2010SE Single Quadrupole Mass Spectrometer | Precision Hydrogen Trace |
Agilent Intuvo 9000 GC | Precision Series |
Agilent 7890 Series GC | Precision Series |
Agilent 1260 Infinity II Diode Array Detector | Solaris XE 35 |
Ellutia 200 Series GC | Precision Hydrogen Trace for carrier gas |
SCIEX Triple Quad™ or QTRAP® 6500+ system | Genius 1024, Infinity 1031 |
In addition to Peak Scientiifc's Precision series of gas geneartors for gas chromatography, the Solaris XE 35 nitrogen generator could also be used for terpene testing with LC-MS instruments. To discover Peak's full range of gas generators for LC-MS please click here.
Solaris XE 35 nitrogen generator
Pesticide Screening
Pesticide regulations for cannabis cultivation vary depending on the country or state where the cannabis is being grown.This means that pesticide screening is not only necessary for health and safety reasons, it is also often a legal requirement.
Again, Chromatography (either liquid or gas) is the main analytical method used for pesticide screening. Some of the instruments which can be used for pesticide screening include:
Instrument which can be used for Pesticide Screening | Peak Scientific recommended gas solution |
Shimadzu LCMS-8050 triple quadruple mass spectrometer * | Infinity 1051, Genius 1051*, Genius 3051 |
SCIEX ExionLC™ AC HPLC System with the SCIEX QET 4500 LC-MS/MS System | Genius 1024, Genius AB-3G, Infinity 1031 |
Agilent 7000 Series Triple Quadrupole GC/MS | Precision Series |
Agilent 6400 Series Triple Quadrupole LC/MS | Solaris XE 35, Genius XE 35 |
Agilent 6500 Series Accurate-Mass Quadrupole Q-TOF LC/MS | Solaris XE 35, Infinity XE 5010, Genius XE 35, Genius XE 70 |
Agilent GC/MS/MS Pesticides Analyzer | Precision Series |
Agilent Intuvo 9000 GC system | Precision Series |
Agilent 7890B GC system | Precision Series |
Agilent Ultivo triple quadrupole LC/MS | Genius NM32LA, Genius XE 35 |
Agilent 7010B Series triple quadrupole GC/MS system | Precision Nitrogen Trace for Collision Gas, Precision Hydrogen Trace |
Waters Xevo TQ-S Micro | Solaris XE 35, Genius SQ 24 |
Waters Xevo TQ-GC | Solaris XE 35, Genius SQ 24 |
* The Genius 1051 is the recommended Peak solution for both the 8045, 8050 and 8060, and will provide sufficient gas flow when the 8045/8050/8060 is operating in ‘Default Gas Delivery Mode’. When operating in ‘High Flow Gas Delivery Mode’, the gas flow requirement is increased, which may exceed the capabilities of the Genius 1051, in this instance the Genius 3051 is the recommended solution.
At Peak Scientific we have a variety of gas generators which we can recommend for pesticide screening, depending on the instrument you use. Our range of gas solutions include both integrated compressors and compressorless solutions with varying flows, pressures and purities. Contact us now to discover the ideal gas solution for your instrument and application.
Genius XE 35 nitrogen generator
Residual Solvents
Residual solvents are the by-prodcusts which can often be found in processed cannabis. Controlling the amount of residual solvents present in cannabis, and ensuring the amount present remains below the acceptable levels, is important for consumer safety.
Analytical instruments which can be used for residual solvent analysis include:
Instrument which can be used for Residual Solvents testing | Peak Scientific recommended gas solution |
Shimadzu Nexis GC-2030 with HS-20 Headspace Sampler or GCMS-TQ8050 with headspace | Precision Series - Precision Nitrogen Headspace |
Agilent 7890 Series GC | Precision Series |
Agilent Flame Ionization Detector | Precision Series |
Ellutia 200 Series GC | Precision Hydrogen Trace for carrier gas |
Thermo Fisher TRACE 1310 Gas Chromatograph | Precision Series |
Thermo Fisher TriPlus 300 Headspace Autosampler | Precision Nitrogen |
Thermo Fisher Instant Connect Electron Flame Ionization Detector (FID) for TRACE 1300 GC Series | Precision Series |
SCIEX QTRAP 6500+ System | Genius 1024, Infinity 1031 |
For residual solvent analysis with gas chromatography, a generator from our Precision series could be the perfect gas solution. Get in touch to discover which generator would best suit your specific requirements.
Heavy Metals
Depending on the growing medium used for cannabis cultivation, different contaminants can be found in the plants. Sometimes these may be heavy metals such as Chromium, Arsenic and Lead which are toxic, so their presence must be monitored to ensure safety.
Some instruments which are used to monitor the presence of heavy metals in cannabis include:
Instrument which can be used for Heavy Metals testing | Peak Scientific recommended gas solution |
Agilent 7800/7900 ICP-MS | Precision Hydrogen Trace 250cc |
Agilent 8900 Triple Quadrupole ICP-MS | Precision Hydrogen Trace 250cc |
Agilent 5110 ICP-OES | NG5000 or NG5000A |
Thermo Fisher iCAP 7000 ICP-OES | Genius 1053 |
If your application requires hydrogen gas for heavy metal testing, the Peak Scientific Precision Hydrogen Trace 250 may be the best gas solution. Get in touch to find out which gas generator we would recommend to best meet your needs.
Precision Hydrogen Trace 250
Mycotoxins Analysis
Long term storage of cannabis can result in fungal growth (mold) due to the high moisture content of cannabis. Mycotoxins are a toxic secondary metabolit of mold so it important to make sure that cannabis does not contain unacceptable levels of these toxins.
Instruments which can be used for mycotoxins analysis include:
Instrument which can be used for Mycotoxins Analysis | Peak Scientific recommended gas solution |
Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer* | Infinity 1051, Genius 1051*, Genius 3051 * |
SCIEX Triple Quad™ or QTRAP® 6500+ system | Genius 1024, Infinity 1031 |
Thermo Fisher TSQ Altis and TSQ Quantis Triple Quadrupole Mass Spectrometer LC-MS/MS Systems | Solaris XE 35, Genius XE 35 |
Thermo Fisher Q Exactive Hybrid Quadrupole-Orbitrap LC-MS Mass Spectrometer | Solaris XE 35, Genius XE 35, Genius 1022 |
Waters Xevo TQ-GC | Solaris XE 35, Genius SQ 24 |
Waters Xevo TQ-S Micro | Solaris XE 35, Genius XE 35 |
* The Genius 1051 is the recommended Peak solution for both the 8045, 8050 and 8060, and will provide sufficient gas flow when the 8045/8050/8060 is operating in ‘Default Gas Delivery Mode’. When operating in ‘High Flow Gas Delivery Mode’, the gas flow requirement is increased, which may exceed the capabilities of the Genius 1051, in this instance the Genius 3051 is the recommended solution.
At Peak Scientific we have a range of gas generators which can be used as the gas supply solutions for mycotoxins analysis. The gas solution we would recommend for your application depends on the instrument you are using, it's requirements and your need for compressed air. Contact us now to discover your ideal gas solution.
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